2024

• Adams, D.J.*, Barlas, B., McIntyre, R.E., Salguero, van der Weyden, L., Barros A., Vicente, J.R., Karimpour N., Haider A., Ranzani, M., […] and Balmus, G*. (2024) Genetic determinants of genomic stability identified by comprehensive in vivo analyses of micronucleus formation. Nature 627, pages130–136

• L Peruzzotti-Jametti, CM Willis, G Krzak, R Hamel, L Pirvan, R-B Ionescu, JA Reisz, HA Prag, ME Garcia-Segura, V Wu, Y Xiang, B Barlas, AM Casey, AMR van den Bosch, AM Nicaise, L Roth, GR Bates, H Huang, P Prasad, AE Vincent, C Frezza, C Viscomi, G Balmus, Z Takats, JC Marioni, A D’Alessandro, MP Murphy, I Mohorianu, S Pluchino (2024) Mitochondrial complex I activity in microglia sustains neuroinflammation Nature 628, 195–203

• Amir Jassim, Birgit V Nimmervoll, Sabrina Terranova, Erica Nathan, Katherine E Masih, Lisa Ruff, Matilde Duarte, Elizabeth Cooper, Linda P Hu, Gunjan Katyal, Melika Akhbari, Reuben J Gilbertson, Colton Terhune, Gabriel Balmus, Stephen P Jackson, Mariella G Filbin, Anthony Hill, Anarita Patrizi, Neil Dani, Aviv Regev, Maria K Lehtinen, Richard J Gilbertson (2024) Natural language processing charts transcriptome evolution to design combination cancer therapies ioRxiv preprint doi: https://doi.org/10.1101/2024.04.09.585681

2023

• Fang T*, Sun Y., Pearce A.C., Eleuteri S.C., Kemp M., Luckhurst C.A., Williams R, Mills R., Almond S, Burzynski L, Markus N, Lelliott CJ, Karp NA, Adams DJ, Jackson SP, Zhao J, Ganley IG, Thompson PW*, Balmus G*, Simon DK (2023) Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model. Nature Communications 14 (1), 7295

2022

• E Vincendeau, W Wei, X Zhang, C Planchais, W Yu, H Lenden-Hasse, ... SHLD1 is dispensable for 53BP1-dependent V (D) J recombination but critical for productive class switch recombination. Nature communications 13 (1), 1-16 (2022)

• JX Meng, Y Zhang, D Saman, AM Haider, S De, JC Sang, K Brown, ... Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses. Nature communications 13 (1), 1-16 (2022)

2021

• Szebnyi K, Wenger LMD, Sun Y, Dunn AWE, Limegrover CA, Gibbons GM, Conci E, Paulsen O, Mierau SB, Balmus G* and Lakatos A*. Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology. Nature Neuroscience 24, pages 1542–1554 (2021)

• Goold R., Hamilton J., Menneteau T., Flower M., Allen N., Wilkinson H., Thalassinos K., Balmus G.*, and Tabrizi SJ* (2021) FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington’s disease Cell Reports 36 (9), 109649

2020

• Y Sun, AJ Curle, AM Haider, G Balmus (2020) The role of DNA damage response in amyotrophic lateral sclerosis Essays in Biochemistry 64 (5), 847-86

2019

• Ulrich Elling, Michael Woods et al. (2019) Derivation and maintenance of mouse haploid embryonic stem cells. Nature Protocols 14, 1991–2014

• Balmus G, Pilger D et al. (2019) ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks. Nature Communications 10 (87)

2018

• Dev H et al. (2018) - Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells. Nature Cell Biology 20: 954  

• Balmus G, Larrieu D et al. (2018) - Targeting NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome. Nature communications 9 (1), 1700  

• 2017

• Trigg B, Lauer K, Fernandes dos Santos P, Coleman H., Balmus G, Mansur G, Ferguson B (2017) The non-homologous end joining protein PAXX acts to restrict HSV-1 infection. Viruses 9 (11), 342 full text

2016

• Balmus G, Barros AC, Wijnhoven PWG, Lescale C, Hasse HL, Boroviak K, et al. (2016) Synthetic lethality between PAXX and XLF in mammalian development. Genes & Dev. 30:2152-2157

• Lescale C, Hasse HL, Blackford AN, Balmus G, Bianchi JJ, Yu W, et al. (2016) Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination. Cell Reports 16(11), 2967-2997

• McIntyre RE, Nicod J, Robles-Espinoza CD, Maciejowski J, Cai N, Hill J, Verstraten R, Iyer V, Rust AG, Balmus G, Mott R, Flint J, Adams DJ (2016) A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice. G3 6, 82343-2354

• Balmus G, Lim PX, Oswald A, Hume KR, Cassano A, Pierre J, et al. (2016) HUS1 regulates in vivo responses to genotoxic chemotherapies. Oncogene 35: 662–669

• 2015

• Balmus G, Karp NA, Ng BL, Jackson SP, Adams DJ and McIntyre RE (2015) A high-throughput in vivo micronucleus assay for genome stability screening in the mouse. Nature protocols 10(1): 205-215

2014

• Balmus G, and McIntyre RE. (2014). Genetic screens in mice for genome integrity maintenance and cancer predisposition. Curr. Opin. Genet. Dev. 24: 1–7.

2012

• Balmus G, Zhu M, Mukherjee S, Lyndaker AM, Hume KR, Lee J, et al. (2012). Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1. Human molecular genetics 21: 3408–3420.

• Daugherity EK, Balmus G, Saei AA, Moore ES, Abdallah DA, Rogers AB, et al. (2012). The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease. Cell Cycle 11: 1918–1928.

• Qi Q, Huang W, Bai Y, Balmus G, Weiss RS, and August A. (2012). A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice. J Immunol 188: 3611–3619.

2011

• Holloway JK, Mohan S, Balmus G, Sun X, Modzelewski A, Borst PL, et al. (2011). Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis. PLoS Genet. 7: e1002094

• Jinadasa R, Balmus G, Gerwitz L, Roden J, Weiss R, and Duhamel G. (2011). Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice. Journal of Visualized Experiments 50:2598.

2007

• Balmus G, Trifonov VA, Biltueva LS, O'Brien PC, Alkalaeva ES, Fu B, et al. (2007). Cross-species chromosome painting among camel, cattle, pig and human: further insights into the putative Cetartiodactyla ancestral karyotype. Chromosome Research 15: 499–514.

2006

• Di Berardino D, Nicodemo D, Coppola G, King AW, Ramunno L, Cosenza GF, Iannuzzi L, Di Meo GP, Balmus G, and Rubes J. (2006). Cytogenetic characterization of alpaca (Lama pacos, fam. Camelidae) prometaphase chromosomes. Cytogenetic and Genome Research 115: 138–144.

• Basset P, Yannic G, Yang F, O'Brien PCM, Graphodatsky AS, Ferguson-Smith MA, Balmus G, Volobouev VT, and Hausser J. (2006). Chromosome localization of microsatellite markers in the shrews of the Sorex araneus group. Chromosome Research 14: 253–262.

2004

• Carlan M, Carlan AF and Balmus G (2004). Clonal evolution of a mouse metastatic hemangiosarcoma. Analele Stiintifice ale Universitatii" Alexandru Ioan Cuza" din Iasi Sec. II a. Genetica si Biologie Moleculara 5.1.